Author Topic: Dormant tumor  (Read 2184 times)

gunns

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Dormant tumor
« on: April 18, 2018, 10:26:00 pm »
What’s the longest anyone has heard an AN remaining dormant? Also what’s the slowest known growing rate?  I’ve heard a lot of people die from old age complications without knowing they have an AN.

extropy

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Re: Dormant tumor
« Reply #1 on: April 20, 2018, 01:45:48 pm »
You can download this beautiful paper about growth of VS.
https://pdfs.semanticscholar.org/78f9/d7a8b89428f6d313216a24acc8c648fdb895.pdf

2014 - at age 65 problems with left ear (tinnitus, imbalances, deafness, short-memory problems, etc).
2014 - MR found VS, 3.5 cm circa.
2014 - Exeresis, in Rome, RS approach,  followed by hydrocephalus ... and shunt.
2018 - AN has regrown, volume is 2.6 cm3.
2018 - GK (Humanitas, Milan)

notaclone13

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Re: Dormant tumor
« Reply #2 on: April 20, 2018, 02:53:33 pm »
Thanks for sharing this very informative publication.  Will need to read it a few times to absorb all the information.

extropy

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Re: Dormant tumor
« Reply #3 on: April 26, 2018, 05:10:42 am »
See also the story of this (nine years) dormant VS, that suddenly awakened ....
https://www.ncbi.nlm.nih.gov/pubmed/28722232
--serafino (Rome, Italy)
2014 - at age 65 problems with left ear (tinnitus, imbalances, deafness, short-memory problems, etc).
2014 - MR found VS, 3.5 cm circa.
2014 - Exeresis, in Rome, RS approach,  followed by hydrocephalus ... and shunt.
2018 - AN has regrown, volume is 2.6 cm3.
2018 - GK (Humanitas, Milan)

ANSydney

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Re: Dormant tumor
« Reply #4 on: April 26, 2018, 07:55:18 pm »
When people ask what percentage of tumors grow, you need to ask, "by how much".

From the abstract of the article, "Growth in the first year of observation is a strong predictor of tumor growth". This is why I waited one year before deciding what to do. Nothing else seems to predict growth; not age, sex, presenting symptoms, initial tumor size, tumor location or tumor side.

I like the study since it's from Australia :-)

An interesting thread regarding how many tumors grow can be found on this forum https://www.anausa.org/smf/index.php?topic=23404.msg979773646#msg979773646

The real question is how many tumors grow more that 2, 3, 4, and 5 mm. An even better question is what percentage of tumors need to be treated https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1502035/pdf/sbs16095.pdf.

I should point out that I am not a doctor and the opinions expressed in various published studies do vary widely.

extropy

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Re: Dormant tumor
« Reply #5 on: April 27, 2018, 01:42:30 am »
I should point out that I am not a doctor and the opinions expressed in various published studies do vary widely.

Exactly, they vary widely.

And sometimes interesting things happen.
By chance (!) they discovered the dramatic (fast-growing VS) effect of erythropoietin (EPO)
abstract  www.ncbi.nlm.nih.gov/pubmed/17171109
full-text  https://www.researchgate.net/publication/6629182_Fast-Growing_Vestibular_Schwannoma

see also these
www.ncbi.nlm.nih.gov/pubmed/17429338
www.ncbi.nlm.nih.gov/pubmed?term=11349767

--Serafino (Rome, Italy, not a doctor!)
« Last Edit: April 27, 2018, 09:21:15 am by extropy »
2014 - at age 65 problems with left ear (tinnitus, imbalances, deafness, short-memory problems, etc).
2014 - MR found VS, 3.5 cm circa.
2014 - Exeresis, in Rome, RS approach,  followed by hydrocephalus ... and shunt.
2018 - AN has regrown, volume is 2.6 cm3.
2018 - GK (Humanitas, Milan)