ANA Discussion Forum
Pre-Treatment Options => Pre-Treatment Options => Topic started by: mwatto on September 25, 2022, 03:05:08 am
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Read this today: Stress has been postulated to trigger or contribute to inner ear pathologies but there is little objective evidence. We investigated stress hormones in Ménière's patients and patients with acoustic neuroma. Data were compared with those from a control group of patients with facial spasm. We assayed classic stress hormones including adrenocorticotropic hormone, cortisol, growth hormone and prolactin. We found a strong positive correlation between cortisol and adrenocorticotropic hormone in Ménière patients and patients with acoustic neuroma but no correlation in patients with facial spasm. The data also revealed in female patients with Ménière's disease or with acoustic neuroma an unexpected significant positive correlation between cortisol and prolactin. The data showed the expected negative correlation or no correlation between cortisol and prolactin associated with males and females in the other patient groups. Both cortisol and prolactin increases are known to represent alternative strategies to cope with stress, and our data point to prolactin being possibly more dominant in Ménière's disease and cortisol in acoustic neuroma. These data provide further evidence for modification of different stress hormones in audiovestibular pathologies, which might provide a valuable diagnostic or prognostic tool in the future.
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Do you have a reference for that, Michele? It sounds very interesting!
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Hi Donjehle -its not recent but here you go...
https://pubmed.ncbi.nlm.nih.gov/15925138/
and this on inflammation: https://academic.oup.com/neuro-oncology/article/21/3/314/5155625
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Donjehle the shwannoma cell is a type of glial cell in AN so I take a glial modulator PEA (palmidrol) Herbs of Gold otc but any pharmacy will have and its also available compounded. The PEA works on inflammation especially neuro inflammation- calms overactive glial cells that cause nerve pain eg. Its a natural compound been used since the 50s and no side effects or drug interactions. Its a natural analgesic. https://accurateclinic.com/accurate-education-palmitoylethanolamide-pea/
Essentially I try and calm the CNS and view AN as an inflammatory brain disease. Thats my impression anyway. LDN works in a similar way to PEA to calm inflammation.
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Very interesting article Michele !- thanks for posting. Calming the CNS sounds like a really good idea.
hope you're keeping really well
Stella
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Hi Stella yes all is well- I still get some nerve pain at 3 and a half years but I am pleased to say it seems fine mostly now. Maybe my supplements/herbals etc are working. I am on PEA also at the moment after a non covid respiriatory viral infection.
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I've always believed that stress has more impact on our bodies than we sometimes realize. It's intriguing to see scientific research delving into how stress hormones specifically interact with conditions like Ménière's disease and acoustic neuroma.
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Sounds very plausible.
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Hi yes- I think also stress affects blood pressure and sleep. I find when stressed more blood pressure and probably then intercranial pressure also. We need sleep too as the glymphatic system removes toxic protein secretions.
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Stress can cause lots of problems. I also agree the more sleep you can get, the better. After my surgery I slept quite alot. I think it helped.