ANA Discussion Forum

General Category => AN Issues => Topic started by: gunns on April 18, 2018, 10:26:00 pm

Title: Dormant tumor
Post by: gunns on April 18, 2018, 10:26:00 pm

What’s the longest anyone has heard an AN remaining dormant? Also what’s the slowest known growing rate?  I’ve heard a lot of people die from old age complications without knowing they have an AN.

Title: Re: Dormant tumor
Post by: extropy on April 20, 2018, 01:45:48 pm

You can download this beautiful paper about growth of VS.
https://pdfs.semanticscholar.org/78f9/d7a8b89428f6d313216a24acc8c648fdb895.pdf

Title: Re: Dormant tumor
Post by: notaclone13 on April 20, 2018, 02:53:33 pm

Thanks for sharing this very informative publication.  Will need to read it a few times to absorb all the information.

Title: Re: Dormant tumor
Post by: extropy on April 26, 2018, 05:10:42 am

See also the story of this (nine years) dormant VS, that suddenly awakened ....
https://www.ncbi.nlm.nih.gov/pubmed/28722232
--serafino (Rome, Italy)

Title: Re: Dormant tumor
Post by: ANSydney on April 26, 2018, 07:55:18 pm

When people ask what percentage of tumors grow, you need to ask, "by how much".

From the abstract of the article, "Growth in the first year of observation is a strong predictor of tumor growth". This is why I waited one year before deciding what to do. Nothing else seems to predict growth; not age, sex, presenting symptoms, initial tumor size, tumor location or tumor side.

I like the study since it's from Australia :-)

An interesting thread regarding how many tumors grow can be found on this forum https://www.anausa.org/smf/index.php?topic=23404.msg979773646#msg979773646

The real question is how many tumors grow more that 2, 3, 4, and 5 mm. An even better question is what percentage of tumors need to be treated https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1502035/pdf/sbs16095.pdf.

I should point out that I am not a doctor and the opinions expressed in various published studies do vary widely.

Title: Re: Dormant tumor
Post by: extropy on April 27, 2018, 01:42:30 am

Quote from: ANSydney on April 26, 2018, 07:55:18 pm

I should point out that I am not a doctor and the opinions expressed in various published studies do vary widely.

Exactly, they vary widely.

And sometimes interesting things happen.
By chance (!) they discovered the dramatic (fast-growing VS) effect of erythropoietin (EPO)
abstract  www.ncbi.nlm.nih.gov/pubmed/17171109
full-text  https://www.researchgate.net/publication/6629182_Fast-Growing_Vestibular_Schwannoma

see also these
www.ncbi.nlm.nih.gov/pubmed/17429338
www.ncbi.nlm.nih.gov/pubmed?term=11349767

--Serafino (Rome, Italy, not a doctor!)